Transfer on day 5 or blastocyst

Avoiding a multiple pregnancy is one of Eugin Clinic’s main aims during our daily clinical practice. As we well know, obstetric risks during pregnancy increase significantly when twin pregnancy occurs, and this is even more evident in cases involving older patients.

It is for this reason that after several years of constant improvement and progress in our laboratory, we want to establish, whenever technically possible, the transfer at the blastocyst stage.

Our own results confirm that in oocyte reception cycles the success rate achieved by transferring just 1 embryo at the blastocyst stage (Day 5 or Day 6) is equivalent, or even superior, to the transfer of two embryos using cells at (Day 2 or Day 3).

At present, we consider it appropriate to propose prolonged embryo culture for transfer on Day 5 to those couples who are undergoing treatment with donor eggs and have presented with good embryo fertilisation: 5 or more fertilised embryos (2 pronuclei) the day after ICSI. In IVF cycles with one’s own eggs, the results will depend on several factors; mainly, the woman’s age. In these couples, our team of doctors and biologists will assess the case in a particular way and indicate the transfer at the blastocyst stage when the quantity and the embryonic morphology allow for prolonged culture.

At Eugin we believe that it is not just the embryos on Day 5 that can provide good results. Getting to the blastocyst stage is an embryo selection method for maximizing the results by transfer performed (not per cycle initiated) and is therefore the right choice for those couples who have optimal criteria.

We continue trusting, however, in the transfer on Day 2/Day 3. We believe that transfer at the cell stage is a good option in the cases of couples for whom the risk of reaching Day 5 is too high. For example, in those couples who for different reasons have a low number of fertilised embryos.

It is important to remember that every healthily-developing embryo in good condition on Day 2/Day 3 is capable of resulting in a pregnancy.